GURT was developed in the 1980s and first patented in the early 1990s by Dupont and a company now owned by Syngenta. These were not controversial as they focused on turning on or off a trait, such as resistance to a particular herbicide. It became a public issue in 1995, and became known as “Terminator technology,” when the USDA and a small seed company, Delta and Pine Land Company (acquired by Monsanto in 2007) sought a joint patent on a ‘genetic switch’ designed to protect the unauthorized use of second generation seeds.

Luca Lombardo, an agriculture professor at the University of Basilicata in Italy, explains the intent of the USDA’s version of GURT:

Willard Phelps, official spokesman of the U.S. Department of Agriculture (USDA), in an interview with New Scientist (March 29, 1998) declared that: ‘Our system is a way of self- policing the unauthorized use of American technology. It’s similar to copyright protection’, adding that: ‘This technology is designed to increase the value of proprietary seed owned by US seed companies and to open up new markets in Second and Third World countries’. His words were echoed by Melvin J. Oliver, inventor of the technology, who, in March 1998, said: ‘My main interest is the protection of American technology. Our mission is to protect US agriculture, and to make us competitive in the face of foreign competition. Without this, there is no way of protecting the technology.

News of the technology ignited a firestorm of opposition around the world, with opponents (who coined the “terminator” name) claiming it was yet another way for large agriculture firms to gain control over the world’s food supply.  The strongest criticism revolved around the potential impact of the technology on small farmers in third world nations, where seed saving and planting remains a common practice because of the higher cost of more technologically advanced seeds that yield much more. This differs substantially from modern agriculture operations, which prefer hybrid seeds bred for specific traits that aren’t guaranteed to be passed on to their offspring. Several analyses examined the impact that GURTs might have in developing countries, predicting it could “increase the polarization between commercial and subsistence farmers, as well as between developed and developing regions and societies” (here and here and here).

Karen Wright and John Clark wrote for Discover Magazine:

The scope of the problem is unimaginably vast: More than 1 billion people rely on saved seed in developing countries each year. Two-thirds of the population of sub-Saharan Africa subsist on small, low-production farms. Critics contend that once terminator technology takes hold, it will become tied to every other improvement in plant development, so farmers who are unwilling or unable to pay for new seed will be stuck with outdated, inferior varieties.

“It’s climb on the terminator platform, or stay on the sidelines with your old technology and hope you survive,” says Pat Mooney, executive director of the ETC Group, an advocacy organization in Winnipeg, Manitoba. Even if terminator-seed purchases are subsidized, he says, dependence on them could become devastating.

Anti-GMO NGOs united in virulent opposition. Canadian Biotechnology Action Network wrote:

If Terminator is commercialized, corporations will likely incorporate sterility genes into all their seeds. That’s because genetic seed sterilization would secure a much stronger monopoly than patents — instead of suing farmers for saving seed, companies are trying to make it biologically impossible for farmers to re-use harvested seed.

In the wake of the backlash, seed companies pledged to withhold the technology from commercial applications. Monsanto was among those companies, making a commitment in 1999 not to commercialize sterile seed technology.

But in 2006–as Monsanto was in the process of buying Delta and Pine Land Company– critics accused the St. Louis company of revising its pledge to only apply to food crops, leaving open the possibility of using the technology on tobacco or cotton.

Monsanto’s current pledge:

We remain committed not to commercialize sterile seed technology in food crops. After consulting with international experts and sharing many of the concerns of small landholder farmers, Monsanto made a commitment in 1999 not to commercialize sterile seed technology in food crops. We stand firmly by this commitment. We have no plans or research that would violate this commitment in any way

While critics point to the potential negative impact of this technology on seed-saving farmers, there are benefits that could be gained through the use of this technology. Terminator technology could guarantee that GMO seeds would not spread to neighboring fields, what’s known as cross pollination, often framed as ‘contamination’ by organic farmers and GMO critics. Wrote Heidi Ledford in Nature:

In a strange twist of fate, terminator technology has begun to look more appealing to environmentalists. Organic farmers want ways to keep genetically engineered crops from contaminating their fields, and food-safety groups are concerned about contamination of food crops with products from a new generation of crops engineered to produce chemicals or pharmaceuticals. By ensuring that genetically modified plants survive for only one planting, “that technology would have alleviated a lot of environmental concerns”, says Holman.

There are also potential pharmaceutical uses for the technology, including the development of “bioreactor” plants modified to produce vaccines or to serve as diagnostic tools.  Mark Lynas, a visiting fellow at Cornell University and Lúcia de Souza, plant biologist and vice president of the Brazilian National Association of Biosafety wrote:

A continued ban on GURT may sound sensible and precautionary, but could harm our potential to develop lifesaving vaccines and environmentally beneficial crops. Scientists should be allowed to conduct research, and society can later decide – through open, inclusive and democratic debate – how or if these technologies are later deployed more widely.

More than 25 years after its development, so-called terminator seed technology has never been introduced commercially. And while it is unclear if that will ever change, biotechnology firms have not entirely given up on it. Layla Katiraee, molecular geneticist, wrote:

The number of patents on GURTs by public and private institutions/companies has not ceased, suggesting that companies are still seeking the “development of alternative strategies to prevent the unauthorized use of patented seeds and plant varieties.

There is also a chance that Brazil will become the first nation to allow the limited use of terminator technology within its borders.

Whether a terminator seed is even needed is a matter of debate. Kevin Folta, chair of the horticultural sciences department at the University of Florida, has written that hybrid seeds, favored by most farmers, already perform a similar function:

However, if a farmer were to save seeds from the hybrid the genetics would scramble again.  The next generation would produce plants where there was no genetic uniformity.  Most plants would have deleterious traits, maybe poor resistance to disease, bad yield or unmarketable corn quality.  So in all fairness, hybrids are also functionally “terminators” in that they require the farmer to repurchase seeds every year.